Concentration and sources of polycyclic aromatic hydrocarbons in some commercial herbal drugs used for cholera treatment in southwest Nigeria

Akintelu Sunday Adewale, Olugbeko Seyifunmi Charles, Folorunso Femi Adekunle, Oyebamiji Abel Kolawole, Folorunso Aderonke Similoluwa

Abstract

The aim of this study was to investigate the cancer risk that could be incurred from the use of some anti-cholera herbal drugs sold in Southwest Nigeria. Three most popular anti-cholera herbal drugs were studied. The cancer risk estimation for the drugs at studied population ranges from 7.119 to 0.338 x 10-8 in children, 9.563 to 0.129 x 10-8 in preteen and 9.541 to 5.196 x 10-8 in adult. The cancer risk estimated values are below the USEPA set value 1 x 10-6. This established that the use of these herbal drugs might not lead to cancer if consumed at low dosage.

Keywords

cancer risk; traditional medicine; cancer risk estimation; anti-diarrhea and toxicity

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