Hybrid-stabilized silver nanoparticles and their biological impact on hospital infections, healing wounds, and wheat cultivation

Tatyana Zheltonozhskaya, Nataliya Permyakova, Tetiana Kondratiuk, Tetyana Beregova, Valeriy Klepko, Bogdan Melnik


The structure and morphology of new biocide compositions based on silver nanoparticles and silica/polyacrylamide hybrids, as well as their diverse biological effects on traditional hospital infections and wound healing and winter wheat cultivation, were studied. The compositions showed a high bactericidal effect against bacteria of the genera Staphylococcus and Pseudomonas, and fungistatic effect against the yeast genus Candida and filamentous fungi of the genera Aspergillus, Cladosporium, Penicillium, Exophiala, and Fusarium. They also showed high activity in wound healing in rats and significantly changed the rate of development of winter wheat plants due to presowing treatment of seeds.


polymer/inorganic hybrid; silver nanoparticles; structure; morphology; biological impact

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