7-Substituted pyrrolo[2,3-d]pyrimidines for the synthesis of new 1-deazapyrimido[1,2,3-cd]purines

Authors

  • Lyubov Muzychka
  • Iryna Yaremchuk
  • Oksana Muzychka
  • Oleg Smolii Institute of Bioorganic Chemistry and Petrochemistry of NAS of Ukraine

DOI:

https://doi.org/10.17721/fujcV5I2P15-23

Keywords:

pyrrolo[2, 3-d]pyrimidine, iodolactonization, 5, 6-dihydro-4H-1-deazapyrimido[1, 2, 3-cd]purine, cyclizations

Abstract

Few examples of new heterocyclic 1-deazapyrimido[1,2,3-cd]purine derivatives were synthesized by intramolecular cyclization of methyl 7-(oxiran-2-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylates. The latter were obtained by iodolactonization of 7-allylpyrrolo[2,3-d]pyrimidine-6-carboxylic acids.

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Published

2017-12-30

Issue

Vol. 5 No. 2 (2017): Proceedings of the IX International scientific conference “Kyiv-Toulouse”

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Articles

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